AWS HPC Blog
Category: Amazon EC2
Resilient HPC and ML on AWS: Running Tightly Coupled Workloads on Spot Instances
This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. This post was contributed by Santosh Kumar, Bhagyaraju Kasina, Dr. Sandeep Sovani and Dr. Max Starr Researchers and engineering teams running High Performance Computing (HPC) jobs face a constant […]
Transforming HPC Operations with Intelligent Workload Orchestration on AWS
This post was contributed by Manu Pillai, Gloria Macia and Natalia Jimenez, PhD Organizations running high-performance computing (HPC) workloads today operate largely as they have for decades: users manually specify required compute specifications for each of their jobs. Users spend valuable time analyzing workload requirements, selecting instance types, and troubleshooting infrastructure issues – time that […]
High Throughput Scheduling for Financial Services with YellowDog HTS on AWS
This post was contributed by Kirill Bogdanov (Pr. Solutions Architect at AWS) and Alan Parry, (CTO at YellowDog). Large-scale compute grids sit at the heart of modern financial services operations. They power overnight batch runs for regulatory risk and prepare traders for the coming day. During trading, the same grids drive intraday ‘value at risk’ […]
Cost-effective and scalable Oxford Nanopore Technologies primary analysis with Nextflow and Amazon EC2 G Instances
This post was contributed by Stefan Dittforth and Michael Mueller Introduction Oxford Nanopore Technologies (ONT) sequencing enhances genome analysis in research and healthcare with its ability to produce long-read sequencing data in real-time. Long reads improve our ability to detect structural variation, resolve repetitive regions, perform haplotype phasing and analyze full-length transcripts, providing a more […]
A Technical Deep Dive into Amazon EC2 Hpc8a Performance for Engineering and Scientific Workloads
High performance computing (HPC) workloads continue to grow in scale and complexity. Whether simulating airflow over an aircraft wing, modeling structural behavior under load, or performing crash simulation and multi-physics analysis, these workloads demand sustained compute throughput, high memory bandwidth, and efficient scaling across large clusters. Improvements in any one of these dimensions can reduce […]
Scaling life sciences research by deploying AWS ParallelCluster and AWS DataSync
This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. In life sciences research, managing large-scale computational resources and data efficiently is important for success. However, traditional on-premises environments often struggle to meet these requirements effectively. This post […]
Meet the Advanced Computing team of AWS at SC25 in St. Louis
This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. We want to empower every scientist and engineer to solve hard problems by giving them access to the compute and analytical tools they need, when they need them. Cloud […]
AWS re:Invent 2025: Your Complete Guide to High Performance Computing Sessions
This post references AWS ParallelCluster. Check out AWS Parallel Computing Service (AWS PCS), our new managed Slurm service for running HPC and AI workloads on AWS. AWS re:Invent 2025 returns to Las Vegas, Nevada on December 1, uniting AWS builders, customers, partners, and IT professionals from across the globe. This year’s event offers you exclusive […]
Petrobras optimizes cost and capacity of HPC applications with Amazon EC2 Spot Instances
Discover how Petrobras and Universidade Federal Fluminense (Rio de Janeiro — Brazil) developed an innovative HPC solution on AWS, leveraging Spot Instances to optimize costs. Explore the automations in place to avoid interruptions and use the lowest-cost instances available.
Application deep-dive into the AWS Graviton3E-based Amazon EC2 Hpc7g instance
In this post we’ll show you application performance and scaling results from Hpc7g, a new instance powered by AWS Graviton3E across a wide range of HPC workloads and disciplines.






