Variants

In life sciences, discovering molecular variations (SNPs and Indels) among individual microbes, plants, animals, and humans is a critical component of scientific innovations. As a known example, scientists have been sequencing coronaviruses and discovered different variants such as alpha, delta, omicron and more. The faster the molecular variations are discovered; the faster the scientists will find solutions for global problems in plants, animals, microbes, humans and other organisms.

Karyosoft's next generation Variants platform key benefits

1. Faster (hours vs days) and can save up to 168 days for 96 samples (https://www.karyosoft.com/uc-davis-testimonial )
2. Being web-based, the users can access Variants on any browser and any device.
3. With a user-friendly interface, Variants can be operated by anyone with any level of computational skills with just 5 clicks.
4. Flexibility to use single or multiple samples by uploading public or private data
5. With an integrated queue manager, the users can run any number of jobs and learn the status of each job.
6. Simple uploading of only reference genome in fasta, gff3 and paired end sequence data of your samples in fastq (any number).
7. Flexibility to use single or multiple samples by uploading the public or private data directly from NCBI-SRA databases or through FTP link/AWS-S3 bucket.
8. The users have options for changing the parameters; if not, the users can automate to run with default parameters.
9. Integrated QC report for all your samples and will get 11 different quality parameters for your sample sequence data.
10. Download all files such as indexed reference, samples, BAM files, VCF with annotations and more for other downstream applications.

The discovered mutations can be used for designing custom chip with highly informative SNPs/Indels for population screening, primer designing around mutations for amplicon sequencing, direct genotyping of your core population to discover allelic status from a single genomic locus through whole genome wide.