The XetaBase Annotations service provides a comprehensive, production-grade genomic annotation and knowledgebase engine, delivering functional, clinical, and population-level insights for genomic and multi-omic data. XetaBase Annotations integrates over 50 public and proprietary data sources to power accurate variant interpretation and discovery across research and clinical genomics.
The XetaBase Annotations module is a scalable, high-performance annotation system designed to enrich genomic data with curated biological, clinical, and population knowledge.
By integrating clinical, functional, and population-level annotations, XetaBase Annotations supports both research and diagnostic applications, streamlining variant discovery. Automated updates ensure access to the latest genomic and biomedical knowledge, while custom annotation options allow institutions to incorporate private or domain-specific datasets to extend interpretive power.
Ideal for clinical laboratories, biopharma, and population genomics programmes, the XetaBase Annotations service delivers traceable, version-controlled, and FAIR-compliant annotations, enabling reproducibility, interoperability, and confidence in genomic interpretation workflows.
Highlights
Comprehensive Data Integration - Combines 50+ public and licensed data sources covering gene, variant, disease, pharmacogenomic, and regulatory annotations.
Automated and Scalable - Performs real-time annotation of millions of variants during ingestion or reanalysis, ensuring up-to-date biological context.
Customisable Knowledgebase - Extendable with internal or project-specific annotations to support bespoke research or clinical requirements.
AWS Marketplace now accepts line of credit payments through the PNC Vendor Finance program. This program is available to select AWS customers in the US, excluding NV, NC, ND, TN, & VT.
Pricing is based on the duration and terms of your contract with the vendor. This entitles you to a specified quantity of use for the contract duration. If you choose not to renew or replace your contract before it ends, access to these entitlements will expire.
Additional AWS infrastructure costs may apply. Use the AWS Pricing Calculator to estimate your infrastructure costs.
XetaBase Annotations is licensed on a contract basis, and you choose your billing period. Both dimensions cover the same annotation licence; they differ only in term length. The annual licence runs for one year, while the monthly licence runs for one month. Pricing scales by the number of units you buy, so you set quantity to match your needs. Pick the shorter monthly term for near-term or trial use, or the annual term for a longer commitment. The two options are independent term choices, not feature tiers.
Top-of-mind questions for buyers
What does one unit of the XetaBase Annotations licence represent for billing?
A unit is one licence for the XetaBase Annotations capability, which provides variant annotation of genomic data. You add units to match your workload. The annotation tooling draws on aggregated reference data from over 40 sources to annotate genomes and variants in a consistent way.
How does billing differ between the monthly licence and the annual licence?
The monthly licence covers one month of use per unit, and the annual licence covers twelve months per unit. Both charge for the same annotation capability. The monthly option suits short-term or trial use with less commitment. The annual option covers a full year under one licence period.
If I need more annotation capacity later, how does my cost change?
Pricing scales with the number of units you purchase, so cost rises as you add units. There are no usage tiers or included-amount thresholds in the table. To increase capacity, you add units under your chosen term rather than crossing an automatic tier boundary.
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Our support hours are from 8 am to 6 pm, Monday to Friday. For any queries or assistance, you can reach us through our service desk or by email at support@zettagenomics.com. Please note that response times and support coverage may vary depending on your purchase plan, and we are happy to discuss any adjustments that may be required.
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The XetaBase platform is a complete genomics ecosystem to power insights and discovery. Available products - XetaBase Enterprise, XetaBase Variant Store and XetaBase Annotations
The XetaBase Variant Store is a high-performance genomic data repository designed for efficient storage, querying, and interpretation of variant data at scale. It provides researchers and clinicians with rapid access to aggregated and individual variant-level information across large cohorts.
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